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Mako, who has directed East West Players since its inception in 1965, has resigned as the group’s artistic producing director. The board of directors “came out with guidelines I could not live with,” Mako said Tuesday. “The guidelines covered play selection, personnel and casting.” Mako will “pursue new personal creative endeavors,” according to a statement released by East West administrator Michele Garza. Mako said those endeavors will be concentrated in film, “something we had failed to do in the past.” A search is under way for a new leader of the Hollywood-based group, Southern California’s leading Asian-American theater company.